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English: The inhibitory mechanism of serpins involved a large conformation change.The serpin (white) first binds a protease (grey) with the reactive centre loop (blue). When cleaved by the protease, this loop rapidly inserts into the A-sheet (light blue), deforming and inhibiting the protease. (PDB: 1K9O​, 1EZX​)
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Fonte Obra propre
Autor Thomas Shafee

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depicts English

copyright status English

copyrighted English

inception English

13 desembre 2015

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Data/OraImajetaMesurasUsorComenta
aora23:04, 19 marto 2016Imajeta per revisa de 23:04, 19 marto 20163,000 × 3,000 (2.83 MB)Evolution and evolvabilityColour tweaks
09:55, 22 desembre 2015Imajeta per revisa de 09:55, 22 desembre 20151,800 × 1,868 (1.13 MB)Evolution and evolvabilityHigher resolution and darker grey for protease
00:36, 20 desembre 2015Imajeta per revisa de 00:36, 20 desembre 20151,083 × 1,125 (498 KB)Evolution and evolvabilityblue arrow (inkeeping with Serpin mechanism.png scheme)
11:52, 13 desembre 2015Imajeta per revisa de 11:52, 13 desembre 20151,083 × 1,125 (496 KB)Evolution and evolvabilityA-sheet colour
11:33, 13 desembre 2015Imajeta per revisa de 11:33, 13 desembre 20151,150 × 1,111 (462 KB)Evolution and evolvabilityCross-wiki upload from en.wikipedia.org

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